"Cosmetics, tear film lipid layer test results are distorted"…Korea's First Identification

Jul 16, 2024

'Cosmetics, tear film lipid layer test results are distorted'…Korea's First Identification
LED cotton light source and various cosmetic contamination patterns observed with a micro light microscope. (A) marbling, (B) too many colors, (C) black spots, (D) white spots, (E) dry areas (red arrows).



For the first time in Korea, domestic researchers have revealed the effect of cosmetics on the results of the tear film lipid layer test.

It is important to measure the thickness of the tear film lipid layer to diagnose dry eyes and determine the cause.

A research team led by Hwang Ho-sik, a professor at the Catholic University of Korea's Yeouido St. Mary's Eye Hospital, analyzed 173 tear film lipids using LipiView, a device that measures the thickness of the tear film lipid layer, and a lipid layer observation method developed using its own LED cotton light source and a thin lamp microscope.




The research team confirmed that 29 out of 173 people were contaminated with cosmetic products. The polluters were all women.

The tear film lipid layer contaminated with cosmetics showed various patterns. It was divided into marbling (24.1%), too much color (31.0%), black dot (24.1%), white dot (17.2%), and dry area (3.4%).

As measured by LipiView, the thickness of the tear film lipid layer in the non-contaminated group was 68.0 nm, whereas the contaminated group was thicker at 100.0 nm. On the other hand, there was no significant difference between the two groups in the tear film destruction time.




As a result of measuring the thickness of the tear film lipid layer before and after makeup, there was a significant difference of 95.3 nm during makeup, but 74.6 nm when no makeup was applied.

Professor Hwang stated that "the first study to confirm the effect of cosmetics on tear film lipid layer examination" and "We recommend measurement without makeup for accurate examination.'

The study was published in the July 2024 issue of the prestigious international academic journal Oculus Surface (IF 5.9) in the field of ophthalmology, and was conducted with support from the Health Industry Promotion Agency and the Ministry of Education Research Foundation's mid-sized research support project.




'Cosmetics, tear film lipid layer test results are distorted'…Korea's First Identification
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