Domestic Children and Adolescents 'Severe Atopic Dermatitis' Doubles in 8 Years

Jul 08, 2024

The prevalence of severe atopic dermatitis among children and adolescents in Korea has doubled in eight years.

In addition, children with severe atopic dermatitis were found to have a significantly higher prevalence of chronic systemic diseases such as cardiovascular disease, autoimmune disease, inflammatory bowel disease, and tumors.

Professor Shin Sang-hee of the Department of Pediatrics and Adolescents at Chung-Ang University Hospital, Professor Ahn Kang-mo of Samsung Medical Center, Dr. Kim Sun-woo of LSK Global PS Academic Research Team, and Professor Lee Ji-young of Chuncheon Sacred Heart Hospital recently published a research paper titled 「Increased prevalence of severe atopic dermatitis and concomitant chronic systemic diseases among Korean children and adolescents」.

Based on data from the Health Insurance Review and Assessment Service, the research team analyzed the prevalence of atopic dermatitis and chronic systemic disease patients between the ages of 6 and 20 in Korea between 2011 and 2019.

As a result, the overall prevalence of atopic dermatitis has increased from 2.34% in 2011 to 3.33% in 2019, of which severe atopic dermatitis has doubled from 0.02% in 2011 to 0.04% in 2019, and from 18 to 37 children per 100,000 people over the past eight years.

The proportion of patients with severe atopic dermatitis compared to all atopic dermatitis patients also increased from 0.76% in 2011 to 1.10% in 2019, meaning that the rate of increase in children with severe atopic dermatitis is faster than the rate of increase in all atopic dermatitis patients.

This trend was more pronounced when the scope was narrowed to adolescents aged 13 to 18, with the proportion of severely ill patients to all patients in the 13-18 age group increasing from 1.31% in 2011 to 1.87% in 2019.

Professor Shin Sang-hee's research team compared the prevalence of chronic systemic diseases according to the severity of atopic dermatitis (atopy-free group, mild atopic dermatitis group, and severe atopic dermatitis group) in the entire population of children and adolescents under the age of 20 in Korea.

As a result, it was found that the severe atopic dermatitis group had a significantly higher rate of chronic systemic disease than the other two groups from 2011 to 2019.

Professor Shin Sang-hee said "This study confirmed that severe atopic dermatitis is not a local skin disease but a disease that is often accompanied by systemic chronic diseases."

Professor Shin Sang-hee then emphasized the importance of severe atopic dermatitis in children and adolescents as a prerequisite for chronic systemic disease, and appropriate treatment, including initial intervention and biological treatments, is required before mild atopic dermatitis progresses to severe atopic dermatitis.

Meanwhile, this research paper was sponsored by Lee Kun-hee's research project on childhood cancer and rare diseases, and was published in the latest issue of the SCIE-class journal Allergy Asthma & Immunology Research.



Domestic Children and Adolescents 'Severe Atopic Dermatitis' Doubles in 8 Years


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