Possible death from muscle pain after a radical workout?

Jul 15, 2024

Possible death from muscle pain after a radical workout?
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In the hot summer, there are heatstroke and other diseases that rapidly increase in the kidney internal medicine ward. The age group ranges from young patients who suddenly started high-intensity exercise to manage body fat hidden under cold winter clothes to elderly patients who squat under the hot sun and work in the field for a long time. Their diagnostic name is very unfamiliar from the name '橫紋筋融解症 Rhabdomyolysis'.

Rhabdomyolysis refers to muscles that represent horizontal patterns, and melting means melting, and rhabdomyolysis refers to a syndrome in which muscle cell contents are released into the blood due to rapid destruction of skeletal muscles. In particular, myoglobin, the most important component of muscle cells, can be excreted in large amounts, which can cause severe acute kidney damage by closing the kidney's tubules.

The causes of rhabdomyolysis are largely divided into trauma and non-traumatic. Traumatic causes are literally traumatic (bruised) or direct muscle damage such as long-term muscle compression, long-term floating posture, burns, and electric shock. Non-traumatic causes are muscle ischemia (due to high-intensity exercise that is not fit), heat stroke or hyponatremia, alcohols and drugs, toxic substances, metabolic myopathy or endocrine diseases (hyperthyroidism and hypothyroidism, adrenal abnormalities).

The main symptoms are muscle pain, muscle weakness, and cola-colored urine. Usually, it is difficult to lift the limbs due to decreased muscle strength in the thighs and shoulders, or the urine is brown or red, so you may visit the hospital thinking it is hematuria. If these symptoms appear within hours or days after trauma or excessive exercise, it is right to visit the hospital quickly.

Diagnosis is made through blood tests and urine tests along with symptoms. If blood creatin kinase (CK) levels rise more than 10 times above the normal range, it can be diagnosed, and myoglobinuria can be confirmed in urine tests.

Rhabdomyolysis has a very good treatment prognosis if it is actively treated in the early stages, but if complications such as missed treatment or acute kidney injury are accompanied, life is at risk. The mortality rate from rhabdomyolysis has been reported to be 8-10%, and when acute renal injury is accompanied, the mortality rate increases to 42%, because emergency dialysis or multiple organ failure is caused.

Therefore, treatment to prevent acute renal injury is given priority to rhabdomyolysis. The most important thing in treatment is sufficient fluid supply, and if there is an electrolyte abnormality, it is necessary to prevent kidney damage as much as possible while correcting it. Emergency dialysis treatment may be required if acute renal injury progresses due to complications or electrolyte abnormalities are not controlled.

In addition, if the degree of muscle damage is severe, compartment syndrome may occur and surgical treatment may be required. Compartment syndrome is a disease in which muscle pressure increases as muscles swell, compress arteries, and block blood supply at the ends, causing necrosis of muscles and other soft tissues within 4-8 hours.

Min Ji-won, a professor of kidney medicine at the Catholic University of Korea's Bucheon St. Mary's Hospital, advised "To prevent rhabdomyolysis, it is important not to suddenly exercise excessively, but to increase the amount of exercise step by step according to your ability." In addition, in the hot summer, it is essential to refrain from outside activities and to take sufficient rest and water in between activities."

※How to exercise to prevent rhabdomyolysis

- Start with light exercise according to your physical strength

-Slowly increase exercise intensity and frequency

-Avoid strenuous exercises or immobility that strain your muscles

-When you exercise, make sure to drink plenty of fluids and take a break

Possible death from muscle pain after a radical workout?
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