Professor Bae Geon-ho of Seoul National University Hospital, 'Global Medical Scientist Training Project'
Jul 14, 2024
Professor Bae Geon-ho, a medical researcher at Seoul National University Hospital, recently announced that he was selected as the subject of global training for medical scholars in the 「Global Medical Scientist Training Project」. With a total of 450 million won in research funds, the research institute affiliated with Harvard Medical School in Boston plans to conduct research from September 2024 to December 2026.
Supported by the Ministry of Health and Welfare and organized by the Korea Health Industry Promotion Agency, the 「Global Doctor Scientist Training Project」 is to produce world-class researchers 10 years later by fostering convergent global innovative talents in the biomedical field.
Professor Bae Geon-ho, who specializes in the retina, plans to study 'retinal fibroblast disease' through single cell omics analysis at Massachusets Eye and Ear, the Schepens Eye Research Institute, a Harvard-affiliated research institute.
Retinal fibro-angiogenesis is a kind of wound healing phenomenon, and is one of the main causes of irreversible vision loss or blindness through the process of proliferation, contraction, and denaturation of various cells. It is accompanied by macular degeneration, retinal detachment, and diabetic retinopathy, whose prevalence is gradually increasing in Korea. The disease has a large difference in prognosis, such as recurrence after surgery, because the cell composition of the fibrous vascular membrane varies depending on the patient's condition.
Despite advances in treatment technology so far, there has been no other treatment options other than traditional surgery for the past few decades.
Professor Bae will conduct a single-cell omics analysis study from samples taken from the retina of various races and a fibro-vascular mouse model. It is expected that a new turning point in the treatment of refractory retinal disease caused by fibrosis can be reached if the molecule that regulates the key step in forming fibroblast tissue, 'interlobe metastasis process' can be identified.
Professor Bae Geon-ho said, "The goal of this global medical scientist training project is to reveal the composition and disease of fibroblast tissue cell groups and to discover new drug candidates. It is expected that the research in the field of single cell omics for retinal disease will provide a new paradigm for the diagnosis and treatment of intractable retinal disease tailored to patients."
Supported by the Ministry of Health and Welfare and organized by the Korea Health Industry Promotion Agency, the 「Global Doctor Scientist Training Project」 is to produce world-class researchers 10 years later by fostering convergent global innovative talents in the biomedical field.
Professor Bae Geon-ho, who specializes in the retina, plans to study 'retinal fibroblast disease' through single cell omics analysis at Massachusets Eye and Ear, the Schepens Eye Research Institute, a Harvard-affiliated research institute.
Retinal fibro-angiogenesis is a kind of wound healing phenomenon, and is one of the main causes of irreversible vision loss or blindness through the process of proliferation, contraction, and denaturation of various cells. It is accompanied by macular degeneration, retinal detachment, and diabetic retinopathy, whose prevalence is gradually increasing in Korea. The disease has a large difference in prognosis, such as recurrence after surgery, because the cell composition of the fibrous vascular membrane varies depending on the patient's condition.
Despite advances in treatment technology so far, there has been no other treatment options other than traditional surgery for the past few decades.
Professor Bae will conduct a single-cell omics analysis study from samples taken from the retina of various races and a fibro-vascular mouse model. It is expected that a new turning point in the treatment of refractory retinal disease caused by fibrosis can be reached if the molecule that regulates the key step in forming fibroblast tissue, 'interlobe metastasis process' can be identified.
Professor Bae Geon-ho said, "The goal of this global medical scientist training project is to reveal the composition and disease of fibroblast tissue cell groups and to discover new drug candidates. It is expected that the research in the field of single cell omics for retinal disease will provide a new paradigm for the diagnosis and treatment of intractable retinal disease tailored to patients."
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