Professor Lee Hyun-woo at Boramae Hospital in Seoul 'Air Pollutants, Respiratory Health Complex Effects' Investigation
Jul 30, 2024
Lee Hyun-woo, a professor of respiratory medicine at Seoul Boramae Hospital, said in the recent issue of the Asian Pacific Society of Respiratory Diseases that changes in various air pollutant concentrations have a complex effect on small airway dysfunction.
Small airway dysfunction is associated with various respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD). Small airway dysfunction can lead to worsening and acute exacerbation of these conditions.
Although the effects of air pollution on lung function are well known, the complex effects of multiple air pollutants in real-world environments have not been sufficiently studied. This study is the first to systematically investigate the effects of complex changes in several air pollutants on small airway dysfunction.
The research team estimated annual changes in the concentration of nitrogen dioxide (NO2), ozone (O3), ultrafine dust (PM2.5), sulfur dioxide (SO2), and carbon monoxide (CO) in 29,115 people using the Korean National Health and Nutrition Survey (KNHANES) DB from 2010 to 2018, and analyzed their association with small airway dysfunction.
The research team evaluated the combined effects using multivariate regression and g-Computing models, and found that the combined effects of annual changes in several air pollutants were significantly associated with small airway dysfunction independently. In particular, changes in concentrations of NO2, O3, PM2.5, SO2, and CO were associated with an increased risk of small airway dysfunction.
Professor Lee Hyun-woo emphasized that "this study is an important study that systematically identifies the complex effects of air pollutants on respiratory health" and that "there is a need to approach various pollutants simultaneously when establishing air pollution management policies".
Small airway dysfunction is associated with various respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD). Small airway dysfunction can lead to worsening and acute exacerbation of these conditions.
Although the effects of air pollution on lung function are well known, the complex effects of multiple air pollutants in real-world environments have not been sufficiently studied. This study is the first to systematically investigate the effects of complex changes in several air pollutants on small airway dysfunction.
The research team estimated annual changes in the concentration of nitrogen dioxide (NO2), ozone (O3), ultrafine dust (PM2.5), sulfur dioxide (SO2), and carbon monoxide (CO) in 29,115 people using the Korean National Health and Nutrition Survey (KNHANES) DB from 2010 to 2018, and analyzed their association with small airway dysfunction.
The research team evaluated the combined effects using multivariate regression and g-Computing models, and found that the combined effects of annual changes in several air pollutants were significantly associated with small airway dysfunction independently. In particular, changes in concentrations of NO2, O3, PM2.5, SO2, and CO were associated with an increased risk of small airway dysfunction.
Professor Lee Hyun-woo emphasized that "this study is an important study that systematically identifies the complex effects of air pollutants on respiratory health" and that "there is a need to approach various pollutants simultaneously when establishing air pollution management policies".
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