Seoul Bumin Hospital publishes an international academic journal, 'Effect of mobile lifestyle intervention using high-protein dietary alternatives'
Jul 21, 2024
The results of a joint study between Seoul Bumin Hospital (Hospital Director Ha Yong-chan) and BioNutrion (CEO Kim Joo-young) 'The effect of mobile lifestyle intervention on the liver function of patients with metabolic abnormal fatty liver disease (MASLD) has recently been listed in the journal Nutrients.
Founded in 2009, Nutrients is an open-access journal that makes important contributions in nutrition and related research, ensuring the quality of the paper through a rigorous peer review process.
In particular, it covers research related to various academic fields such as biology, medicine, public health, and sports science as well as nutrition.
This study is a pilot randomized controlled trial evaluating the effectiveness of mobile lifestyle intervention combining high-protein dietary alternatives in patients with metabolic abnormal fatty liver disease (MASLD).
Doctor Coach, which was used in the study through mobile lifestyle intervention, is an app that manages metabolic abnormal fatty liver disease using personalized nutrition prescriptions and artificial intelligence-based cognitive behavioral therapy coaching programs.
The subjects of the study were 60 adults who were diagnosed with fatty liver disease with metabolic abnormalities at the Seoul Bumin Hospital Health Examination Center and had a body mass index (BMI) of 25 kg/㎡ or more, who were randomly assigned to the experimental group using mobile apps and high-protein dietary alternatives and the control group receiving standard nutrition education data.
The study lasted for four weeks, and liver enzyme levels, ultrasound results, and anthropometric measurements were measured on the baseline and four weeks later, respectively.
As a result of the study, a significant decrease was observed in alanine aminotransferase (ALT) and gamma glutamyltransferase (GGT) levels (used as an indicator of liver health status) in the experimental group, but there was no significant change between the two groups in weight, contrary to expectations. The actual weight is a combination of moisture, muscle, and fat, and it suggests that fat/muscle ratio should be lost more than simple weight in improving fatty liver. This mobile lifestyle management program, which combines high-protein dietary alternatives, shows the potential to lower fat/muscle ratios more effectively in the short term.
"This study is the first case that lifestyle interventions combining mobile apps and high-protein dietary alternatives can be useful in managing metabolic abnormalities," said Jeong Hoon-jae, head of the Future Medical Research Institute at Bumin Hospital. "We expect that the results of this study will provide a new therapeutic approach to managing patients with metabolic abnormal fatty liver disease."
"We expect the study to be based on real-world data and to be able to present new options for the management of relatively metabolic abnormalities of fatty liver disease," a BioNewtrion official said.
The researchers added that comprehensive and long-term further studies are needed for further confirmation.
Founded in 2009, Nutrients is an open-access journal that makes important contributions in nutrition and related research, ensuring the quality of the paper through a rigorous peer review process.
In particular, it covers research related to various academic fields such as biology, medicine, public health, and sports science as well as nutrition.
This study is a pilot randomized controlled trial evaluating the effectiveness of mobile lifestyle intervention combining high-protein dietary alternatives in patients with metabolic abnormal fatty liver disease (MASLD).
Doctor Coach, which was used in the study through mobile lifestyle intervention, is an app that manages metabolic abnormal fatty liver disease using personalized nutrition prescriptions and artificial intelligence-based cognitive behavioral therapy coaching programs.
The subjects of the study were 60 adults who were diagnosed with fatty liver disease with metabolic abnormalities at the Seoul Bumin Hospital Health Examination Center and had a body mass index (BMI) of 25 kg/㎡ or more, who were randomly assigned to the experimental group using mobile apps and high-protein dietary alternatives and the control group receiving standard nutrition education data.
The study lasted for four weeks, and liver enzyme levels, ultrasound results, and anthropometric measurements were measured on the baseline and four weeks later, respectively.
As a result of the study, a significant decrease was observed in alanine aminotransferase (ALT) and gamma glutamyltransferase (GGT) levels (used as an indicator of liver health status) in the experimental group, but there was no significant change between the two groups in weight, contrary to expectations. The actual weight is a combination of moisture, muscle, and fat, and it suggests that fat/muscle ratio should be lost more than simple weight in improving fatty liver. This mobile lifestyle management program, which combines high-protein dietary alternatives, shows the potential to lower fat/muscle ratios more effectively in the short term.
"This study is the first case that lifestyle interventions combining mobile apps and high-protein dietary alternatives can be useful in managing metabolic abnormalities," said Jeong Hoon-jae, head of the Future Medical Research Institute at Bumin Hospital. "We expect that the results of this study will provide a new therapeutic approach to managing patients with metabolic abnormal fatty liver disease."
"We expect the study to be based on real-world data and to be able to present new options for the management of relatively metabolic abnormalities of fatty liver disease," a BioNewtrion official said.
The researchers added that comprehensive and long-term further studies are needed for further confirmation.
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