"Smoking After Stroke Increases Fracture Risk" Up to 1.8x
Jul 08, 2024
Ischemic stroke is a disease in which brain tissue is damaged and does not function properly due to narrowing or clogging of blood vessels in the brain. The number of stroke patients in Korea continues to increase, and according to statistics from the Health Insurance Review and Assessment Service, the number of stroke patients last year was 657,277, up 6% over the past five years. Since brain cells damaged by stroke are difficult to recover, suffering a stroke leads to poor energy and balance, increasing the risk of fracture. In particular, smoking after suffering an acute ischemic stroke has been shown to significantly increase the risk of fracture.
Professor Chun Dae-young (co-corresponding author) of the Department of Circulatory Medicine at Dongtan Sacred Heart Hospital of Hallym University, Professor Lee Jin-hwa (co-author), Professor Lee Min-woo of Neurology at Hallym University Sacred Heart Hospital (co-corresponding author), and Professor Han Kyung-do of the Department of Information Statistics Insurance and Mathematics at Soongsil University (co-author) confirmed this in the study of 「Asociation Between Changes in Smoking Habits and Incident Fracture After Scientific Stroke」.
The research team analyzed 177,787 people over the age of 40 diagnosed with acute ischemic stroke from January 2010 to December 2016 using medical data from the National Health Insurance Service. Among them, 115,380 non-smokers, 24,798 former smokers, 12,240 smokers after stroke, 3,710 new smokers after stroke, and 21,659 continued smokers before and after stroke.
Of the total survey subjects, 14,991 (8.4%) suffered fractures, of which 2,054 (1.2%) had hip fractures and 7,543 (4.2%) had spinal fractures. As a result of analyzing the risk of fracture after adjusting for variables such as age, physical activity, and underlying disease, it was found that smoking significantly increased the risk of fracture after stroke. Compared to non-smokers, new and persistent smokers had a 1.2 times higher risk of fracture. However, in the case of smoking cessation after stroke, the risk of fracture was not different from that of non-smokers.
In addition, the risk of hip fractures was 1.5 times higher for continuous smokers and 1.8 times higher for new smokers compared to non-smokers, so the risk of hip fractures in new smokers was higher than that of continuous smokers. The risk of spinal fractures was 1.3 times higher in persistent smokers than in non-smokers.
Professor Chun Dae-young explained, "In this study, it was found that continuing to smoke after a stroke or new smoking significantly increased the risk of fracture."In particular, increased risk of hip and spinal fractures seems to have a detrimental effect on maintaining bone strength and integrity, especially in skeletal areas under heavy weight and greater mechanical stress."
Professor Jin-Hwa Lee said, `The results of this study show that smoking cessation education after stroke can significantly reduce the risk of fractures and potentially improve the quality of life for stroke experienced people.'
The paper was recently published in the SCIE-level international journal Journal of the American Heart Association (5.4)'.
Professor Chun Dae-young (co-corresponding author) of the Department of Circulatory Medicine at Dongtan Sacred Heart Hospital of Hallym University, Professor Lee Jin-hwa (co-author), Professor Lee Min-woo of Neurology at Hallym University Sacred Heart Hospital (co-corresponding author), and Professor Han Kyung-do of the Department of Information Statistics Insurance and Mathematics at Soongsil University (co-author) confirmed this in the study of 「Asociation Between Changes in Smoking Habits and Incident Fracture After Scientific Stroke」.
The research team analyzed 177,787 people over the age of 40 diagnosed with acute ischemic stroke from January 2010 to December 2016 using medical data from the National Health Insurance Service. Among them, 115,380 non-smokers, 24,798 former smokers, 12,240 smokers after stroke, 3,710 new smokers after stroke, and 21,659 continued smokers before and after stroke.
Of the total survey subjects, 14,991 (8.4%) suffered fractures, of which 2,054 (1.2%) had hip fractures and 7,543 (4.2%) had spinal fractures. As a result of analyzing the risk of fracture after adjusting for variables such as age, physical activity, and underlying disease, it was found that smoking significantly increased the risk of fracture after stroke. Compared to non-smokers, new and persistent smokers had a 1.2 times higher risk of fracture. However, in the case of smoking cessation after stroke, the risk of fracture was not different from that of non-smokers.
In addition, the risk of hip fractures was 1.5 times higher for continuous smokers and 1.8 times higher for new smokers compared to non-smokers, so the risk of hip fractures in new smokers was higher than that of continuous smokers. The risk of spinal fractures was 1.3 times higher in persistent smokers than in non-smokers.
Professor Chun Dae-young explained, "In this study, it was found that continuing to smoke after a stroke or new smoking significantly increased the risk of fracture."In particular, increased risk of hip and spinal fractures seems to have a detrimental effect on maintaining bone strength and integrity, especially in skeletal areas under heavy weight and greater mechanical stress."
Professor Jin-Hwa Lee said, `The results of this study show that smoking cessation education after stroke can significantly reduce the risk of fractures and potentially improve the quality of life for stroke experienced people.'
The paper was recently published in the SCIE-level international journal Journal of the American Heart Association (5.4)'.
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