"Taking antidepressants and anti-anxiety drugs at the same time is likely to gain weight" Most dangerous for men in their 20s
Aug 21, 2024
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Professor Heo Yeon (first author) of Family Medicine at Eulji University Hospital in Uijeongbu (Hospital President Lee Seung-hoon) and Professor Park Hye-soon (Hospital President Park Seung-il) of Asan Medical Center in Seoul (Hospital President Park Seung-il) surveyed 790,000 adults aged 19-39 who received more than two national health checkups from 2009 to 2019 for the association between antidepressants and anti-anxiety drugs and weight gain.
The survey was conducted by categorizing 79,022 subjects (484,499 males, 307,523 females) into ▲ 77,752 subjects (8.9%), ▲ 93,592 subjects (11.8%), ▲ 128,051 subjects (16.2%), ▲ 499,627 subjects (63.1%) who did not take antidepressants and anti-anxiety drugs.
As a result of the survey, it was found that taking antidepressants and anti-anxiety drugs had a higher risk of gaining more than 10kg per year compared to the unadministered group. The annual weight gain rate of more than 10kg was the highest in the antidepressant and anti-anxiety drugs group at 4.1%, followed by 2.9% in the antidepressant group, 2.4% in the anti-anxiety drug group, and 1.7% in the unadministered group.
By gender, men had a higher annual weight gain rate of more than 10 kg than women. In the case of men, 4.5% of the group taking both antidepressants and anti-anxiety drugs, 3.0% of the group taking antidepressants, 2.5% of the group taking antidepressants, and 1.9% of the group not taking them, 3.7% of the group taking antidepressants, 2.8% of the group taking antidepressants, 2.2% of the group taking antidepressants, and 1.4% of the group not taking them.
In terms of age, two groups, 19-29 years old and 30-39 years old, showed that the 19-29 year-old group had a higher rate of weight gain of more than 10 kg per year. In the 19-29 year olds, 5.4% were taking antidepressants and anti-anxiety drugs, 4.1% were taking antidepressants, 3.2% were taking antidepressants, and 2.0% were not taking them, while in the 30-39 year olds, 3.5% were taking antidepressants and anti-anxiety drugs, 2.4% were taking antidepressants, 1.9% were taking antidepressants, and 1.2% were not taking them.
Professor Heo Yeon explained, "Recently, the use of antidepressants and anti-anxiety drugs has been increasing in young adults""Also, obesity in young adulthood can cause a number of diseases, so be careful about the risk of weight gain in young adults when taking antidepressants and anti-anxiety drugs, and be especially careful in the group of patients at risk of weight gain."."
The study was published in the latest issue of the Journal of Clinical Endocrinology & Metabolism, an international academic journal published by the American Endocrinology Society.
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