'Attractive' osteochondroma 24 times higher risk of developing leg deformity
Sep 11, 2024
Osteochondroma refers to a tumor that occurs between bones and cartilage, and is a benign tumor with cartilage-covered bones protruding. It is most common among bone tumors, especially near the growth plate around the knees of children and adolescents. Since it is a benign tumor, it is not life-threatening, but it is important to diagnose and treat it early because it can cause complications such as bone deformation or nerve compression as the tumor grows.
If one osteochromatoma occurs, it is called 'single osteochromatoma', and if it occurs in multiple sites, it is called 'multiple osteochromatosis'. Multiple osteochondromatosis is known as a genetic disease, and the resulting lower limb deformation is relatively common, and many studies have been conducted so far. On the other hand, little is known about the deformation of the lower extremities caused by single osteochromatoma, so research is needed.
Accordingly, a research team led by Professor Sung Ki-hyuk of orthopedic surgery at Seoul National University Bundang Hospital (first author Oh Seung-tak, major in orthopedic surgery) conducted a study to prove that lower limb deformation can occur even in patients with single osteochondroma in childhood and adolescence, and to find out the risk factors. As a result of analyzing 83 patients with single osteochondroma around the knee, lower limb deformation was observed in 8 out of 83 patients (9.6%). Of the eight patients with lower limb deformation, three had lower limb immobility (difference in leg length), two had O and X legs, and three had lower limb immobility and O and X legs.
In addition, all patients who developed lower limb deformity were found to have 'non-hardy' osteochondroma. Osteochondroma is divided into a flat shape without a stem 'non-mild' and a stem 'mild', and according to the research team, the risk of developing lower limb deformation was 24 times higher in the case of non-mild compared to the case of mild. The patient's gender, age, location of bone tumor, and distance between tumor and growth plate, which were examined as other risk factors, were not significantly associated with the occurrence of lower limb deformation.
Professor Sung Ki-hyuk explained, "As osteochondroma is the most common benign bone tumor, it is often easily subject to resection for pain or cosmetic reasons, but the patient's leg alignment was neglected.""In patients with atherosclerotic osteochondroma, there is a high risk of lower limb deformation, so the alignment of the legs should be carefully observed." he said.
Meanwhile, the results of this study were published in the SCI-level international journal 『Journal of Orthopaedic Surgery and Research』.
If one osteochromatoma occurs, it is called 'single osteochromatoma', and if it occurs in multiple sites, it is called 'multiple osteochromatosis'. Multiple osteochondromatosis is known as a genetic disease, and the resulting lower limb deformation is relatively common, and many studies have been conducted so far. On the other hand, little is known about the deformation of the lower extremities caused by single osteochromatoma, so research is needed.
Accordingly, a research team led by Professor Sung Ki-hyuk of orthopedic surgery at Seoul National University Bundang Hospital (first author Oh Seung-tak, major in orthopedic surgery) conducted a study to prove that lower limb deformation can occur even in patients with single osteochondroma in childhood and adolescence, and to find out the risk factors. As a result of analyzing 83 patients with single osteochondroma around the knee, lower limb deformation was observed in 8 out of 83 patients (9.6%). Of the eight patients with lower limb deformation, three had lower limb immobility (difference in leg length), two had O and X legs, and three had lower limb immobility and O and X legs.
In addition, all patients who developed lower limb deformity were found to have 'non-hardy' osteochondroma. Osteochondroma is divided into a flat shape without a stem 'non-mild' and a stem 'mild', and according to the research team, the risk of developing lower limb deformation was 24 times higher in the case of non-mild compared to the case of mild. The patient's gender, age, location of bone tumor, and distance between tumor and growth plate, which were examined as other risk factors, were not significantly associated with the occurrence of lower limb deformation.
Professor Sung Ki-hyuk explained, "As osteochondroma is the most common benign bone tumor, it is often easily subject to resection for pain or cosmetic reasons, but the patient's leg alignment was neglected.""In patients with atherosclerotic osteochondroma, there is a high risk of lower limb deformation, so the alignment of the legs should be carefully observed." he said.
Meanwhile, the results of this study were published in the SCI-level international journal 『Journal of Orthopaedic Surgery and Research』.
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