Identifying risk factors for intractable nosebleeds The incidence of cirrhosis and asthma is 20% higher

Sep 04, 2024

A team of professors Ahn Jae-cheol and Gil Hong-kwon of Cha Medical University Bundang Cha Hospital (Director Yoon Sang-wook) revealed the risk factors for refractory non-bleeding and the location of frequent bleeding. The study was published in the August issue of the SCIE-level international journal (Auris Nasus Larynx).

Non-bleeding is a symptom called 'nopey', divided into anterior and posterior non-bleeding depending on the location where it occurs. Anterior nonhemorrhage is a mild nosebleed caused by anterior capillary hemorrhage, and most of them stop bleeding easily. The problem is when hemostasis is not good and blood continues to bleed. Posterior non-bleeding, in which bleeding occurs in a deep position in the nasal cavity, is difficult to locate and can lead to a lot of bleeding, which can be life-threatening. In particular, posterior hemorrhage, whose location cannot be identified, is classified as intractable hemorrhage, and despite its clinical importance, many studies have not been conducted.

Professor Ahn Jae-cheol and Gil Hong-kwon's team analyzed 766 intractable non-hemorrhagic patients who visited Bundang Cha Hospital's otolaryngology-head and neck surgery from January 2015 to December 2022 for comorbid diseases such as hyperlipidemia, chronic obstructive pulmonary disease, and asthma. As a result, the intersection ratio (OR, Odds Ratio) of comorbidities in refractory nonhemorrhagic patients was 1.13 dyslipidemia, 1.27 cirrhosis, 1.23 obstructive pulmonary disease (COPD), and 1.21 asthma. This means that patients with hyperlipidemia, cirrhosis, chronic obstructive pulmonary disease, and asthma are up to 20% more likely to develop refractory nonbleeding compared to those without hyperlipidemia, cirrhosis, and asthma. In addition, it was confirmed that most of the major bleeding locations are nasal structures, with nasal shelves (middle upper deck) and lower nasal shelves (lower upper deck).

Professor Ahn Jae-cheol of Otolaryngology-Head and Neck Surgery said "Based on this study, we can pre-evaluate the risk factors of patients in case of non-bleeding and predict the possibility of intractable non-bleeding.""We expect it to help with quick and accurate treatment by being able to determine the location of bleeding even in case of a large amount of bleeding.""



Identifying risk factors for intractable nosebleeds The incidence of cirrhosis and asthma is 20% higher
Professors Ahn Jae-chul (left) and Gil Hong-kwon


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