'Parkinson's disease can also be controlled surgically'Deep Stimulation, fewer side effects, no tolerance

Sep 22, 2024

Parkinson's disease caused by lack of dopamine, a neurotransmitter, can be alleviated by 'Deep brain stimulation'. Parkinson's disease patients can control symptoms without side effects without relying on dopamine drugs if they receive deep brain stimulation.

Professor Park Kwang-woo of Neurosurgery at Gachon University Gil Hospital said, `More Parkinson's disease patients need to improve their understanding of deep brain stimulation, which is a reversible surgical treatment", he explained.

Parkinson's disease is caused by the loss of nerve cells that secrete dopamine. Lack of dopamine, a neurotransmitter, has many effects on physical and mental health. Lack of dopamine initially lowers depression or sleep quality. Then, if the secretion of dopamine is further reduced, your hands and feet will tremble and your body's movement will slow down.

If dopamine-related drugs are taken in this state, insufficient dopamine in the brain is supplemented, and the symptoms felt by the patient disappear. The symptoms patients feel at this point are ▲"Often you're walking." ▲"My body keeps moving forward." ▲"I feel the movement of my hands and feet is dull." My hands and feet shake when ▲" is still." ▲"If you sit down for a long time and try to stand up, you can't get up at once." ▲"When I first try to walk, I can't walk away." vary from back to back.

Professor Park Kwang-woo said, `If a patient who lacked dopamine in the brain receives dopamine, the patient can live a normal life. As the tremor disappears and the footsteps become lighter, the energy becomes stronger than anything else. The patient feels the vitality of life again. "But Parkinson's disease is an ongoing disease. The effect of the drug, which initially raised dopamine, will not be the same as before.

Usually, about five years after taking dopamine-related drugs, the duration of drug effects is shortened in most cases. In addition, the side effects of the drug increase. The patient's body is shaken without realizing it. In some cases, psychosis may occur, such as seeing something empty in the eye or hearing strange auditory hallucinations in the ear.

If the condition is like this, the patient needs surgical treatment. Parkinson's disease surgical treatment involves deep brain stimulation by drilling a small hole in the head and inserting an electric needle. The electric needle is implanted in a specific location in the brain related to Parkinson's symptoms, and Parkinson's symptoms are improved through electrical stimulation at this location. In other words, it replaces the effect of dopamine drugs with electrical stimulation.

The problem is that most Parkinson's disease patients rely on drugs for a long time and then learn about deep brain stimulation too late. Parkinson's disease is often not well known to improve symptoms without side effects through surgery.

Although the risks of surgery exist but are highly effective, there is a lack of understanding of deep brain stimulation as a therapeutic option. In addition, deep brain stimulation has a better prognosis for patients who do not progress much with Parkinson's disease.

Deep brain stimulation can improve Parkinson's symptoms such as tremors, stiffness, and slow motion. By replacing dopamine drugs and reducing drug use, side effects and resistance of drugs can be reduced. The quality of life of patients is improved. Above all, this surgery is a reversible treatment that can return to the preoperative state by stopping stimulation or removing the device if necessary.

Professor Park Kwang-woo said, `Recently, some medical staff have argued that deep brain stimulation should be performed three years after Parkinson's disease diagnosis"It is still only recommended in Korea to patients with late Parkinson's disease, where the side effects of Parkinson's drugs have become severe.'

He then added that "A more in-depth discussion is needed in preparation for the increase in Parkinson's disease in an aging society."



'Parkinson's disease can also be controlled surgically'Deep Stimulation, fewer side effects, no tolerance
Professor Park Kwang-woo (right) performing deep brain stimulation.


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