"3D-printed titanium cage with excellent disk surgery effectiveness"
Oct 01, 2024
In the case of severe nerve compression or unstable spinal disease in the neck or waist, a surgery to remove a disk between the upper and lower vertebrae and attach it anew is performed. This induces bone union between the vertebrae by inserting a cage prosthesis into the place where the damaged disk is removed.
Various materials such as ceramic and titanium-coated cages have been used for the material of these spinal cages so far, and the recent development of 3D printing technology has confirmed that 3D-printed porous-Ti (3D-Ti) cages are made and implanted into the spine.
Professor Song Kwang-seop and Ham Dae-woong's orthopedic surgery team at Chung-Ang University Hospital published a clinical research paper (Feasibility of the Non-Window-Type 3D-Printed Porous Titanium Cage in Posterior Lumbar Interbody Fusion) that analyzes the suitability of the '3D-Printed Porous Titanium Cage, a commonly used prosthesis in spinal fusion.
'3D printing cage' is made of titanium, has excellent biocompatibility, implements a porous structure, and adjusts the elastic modulus to a level similar to that of actual bones.
In particular, in this study, there are two types of 3D-printed titanium cages used as disks in spinal fusion surgery: 'window cage' and 'non-window cage'. The research team evaluated and analyzed the effects of patients who underwent these two types of cage spinal fusion a year after surgery.
As a result, 58 out of 61 patients who underwent 3D-printed titanium cage spinal fusion were successfully combined, showing an excellent 95.1% bonding rate. In particular, the bone fusion rate (96.6%) using non-window cages showed relatively high biocompatibility even with the use of bone graft materials compared to the bone fusion rate (93.8%) of window cages, and the sedimentation rate, which is the rate of bone sinking again, was lower (15.6% vs. 3.4%).
As a result, the research team proved through this study that spinal fusion using 3D-printed titanium cage without a window is more effective and has lower complications than cage with a window.
Professor Song Kwang-seop said, "Through this study, a window for bone transplantation is not required in the cage '3D-printed porous-Ti' that is currently used worldwide, and similar bone fusion rates can be obtained through titanium, a cage composition similar to bone, even without a window structure."Considering the biomechanical aspect, a windowless design appears to be useful for bone union. "
"This study can reduce the use of unnecessary osteoclastic agents through the cage in spinal fusion, reducing the cost, time, and effort required for surgery, allowing more effective and successful surgery, and suggesting the direction of the '3D printing porous titanium' cage design in the future," he said.
The research paper was published in the latest issue of the Journal of Bone & Joint Surgery, the best journal in the field of orthopedic surgery.
Various materials such as ceramic and titanium-coated cages have been used for the material of these spinal cages so far, and the recent development of 3D printing technology has confirmed that 3D-printed porous-Ti (3D-Ti) cages are made and implanted into the spine.
Professor Song Kwang-seop and Ham Dae-woong's orthopedic surgery team at Chung-Ang University Hospital published a clinical research paper (Feasibility of the Non-Window-Type 3D-Printed Porous Titanium Cage in Posterior Lumbar Interbody Fusion) that analyzes the suitability of the '3D-Printed Porous Titanium Cage, a commonly used prosthesis in spinal fusion.
'3D printing cage' is made of titanium, has excellent biocompatibility, implements a porous structure, and adjusts the elastic modulus to a level similar to that of actual bones.
In particular, in this study, there are two types of 3D-printed titanium cages used as disks in spinal fusion surgery: 'window cage' and 'non-window cage'. The research team evaluated and analyzed the effects of patients who underwent these two types of cage spinal fusion a year after surgery.
As a result, 58 out of 61 patients who underwent 3D-printed titanium cage spinal fusion were successfully combined, showing an excellent 95.1% bonding rate. In particular, the bone fusion rate (96.6%) using non-window cages showed relatively high biocompatibility even with the use of bone graft materials compared to the bone fusion rate (93.8%) of window cages, and the sedimentation rate, which is the rate of bone sinking again, was lower (15.6% vs. 3.4%).
As a result, the research team proved through this study that spinal fusion using 3D-printed titanium cage without a window is more effective and has lower complications than cage with a window.
Professor Song Kwang-seop said, "Through this study, a window for bone transplantation is not required in the cage '3D-printed porous-Ti' that is currently used worldwide, and similar bone fusion rates can be obtained through titanium, a cage composition similar to bone, even without a window structure."Considering the biomechanical aspect, a windowless design appears to be useful for bone union. "
"This study can reduce the use of unnecessary osteoclastic agents through the cage in spinal fusion, reducing the cost, time, and effort required for surgery, allowing more effective and successful surgery, and suggesting the direction of the '3D printing porous titanium' cage design in the future," he said.
The research paper was published in the latest issue of the Journal of Bone & Joint Surgery, the best journal in the field of orthopedic surgery.
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