Bad chewing of food 'Normal hydrocephalus', high risk of cognitive decline

Oct 11, 2024

'Normal pressure hydrocephalus' is a neurological disease that shows symptoms similar to dementia such as cognitive decline, walking disorders, and incontinence due to an imbalance in cerebrospinal fluid, and occurs in about 2% of the elderly over 70 years of age.

However, for the first time, patients who do not chew food well in patients with 'normal hydrocephalus' were found to be more at risk of cognitive decline than those who did not.

Professor Park Yong-sook and Professor Shin-heon's team of neurosurgery at Chung-Ang University Hospital first presented the results of a study on the correlation between chewing muscles and cognitive function of patients in normal pressure hydrocephalus patients at the Hydrocephalus Meeting 2024 in Nagoya, Japan.

Recent studies have shown that there is a potential link between chewing dysfunction and cognitive decline, and the root's dysfunction plays an important role in maintaining normal chewing patterns and optimal oral health, and these root dysfunction can lead to changes in chewing dynamics, resulting in reduced nutritional intake and subsequent worsening of cognitive impairment.

Professor Park Yong-sook and Professor Lee Shin-heon's team of neurosurgery at Chung-Ang University Hospital evaluated and analyzed the correlation between chewing disorders and cognitive decline in the group of patients using a texture analysis technique that analyzes the texture of images after MRI.

As a result of the study, it was found that the image heterogeneity of 'entropy' and 'pixel gray value', which represent the regression of chewing muscles, were correlated with cognitive functions measured by 'mini-mental state examination (MMSE)' and 'dementia scale'. In addition, both the root regression measures of patients with cognitive impairment, 'entropy' and 'pixel gray value', were found to be higher than those with normal cognitive function.

As a result, the research team of professors Park Yong-sook and Lee Shin-heon confirmed for the first time that degenerative changes in the root of the work in patients with normal pressure hydrocephalus can be associated with cognitive impairment.

Professor Lee Shin-heon said, `Through this study, we can expect the possibility of authoring muscle analysis as a potential tool for predicting cognitive deterioration in patients with normal pressure hydrocephalus.'

Professor Lee Shin-heon then said, `If we plan a strategy to combine surgical treatment (short-circuit surgery), which is the main treatment method, and rehabilitation treatment program considering cognitive impairment in the treatment of patients with normal pressure hydrocephalus, we expect to further optimize the functional improvement of patients with normal pressure hydrocephalus.'

Meanwhile, the research team's research paper was published in the latest issue of the SCIE-level international journal Actaneurochirurgica, and Professor Park Yong-sook and Professor Lee Shin-heon's team are actively conducting patient-specific specialized treatment with 'ventricular-abdominal shunt' and 'local anesthesia lumbar-abdominal shunt' for normal pressure hydrocephalus patients.



Bad chewing of food 'Normal hydrocephalus', high risk of cognitive decline
Professor Park Yong-sook (left) and Professor Lee Shin-heon


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