"Effective needle-free filler injection for skin aging and wrinkle improvement"

Oct 28, 2024

As the skin ages, wrinkles, elasticity, pore expansion, skin thinning and drying appear. These changes are part of the natural aging process, but when the elasticity of the skin decreases, the overall facial contour becomes blurred and the wrinkles become deeper, giving a tired impression and reducing confidence in appearance, which can put psychological burden on social life.

As such, skin aging can affect not only a simple appearance problem, but also the quality of life of an individual, so appropriate treatment is performed depending on the individual, and filler or botulinum toxin injection treatment is performed among hospital treatment methods for skin regeneration.



Meanwhile, a research team led by Professor Hong Ji-yeon and Professor Park Gui-young of the Department of Dermatology at Chung-Ang University Hospital recently published a research paper on the effectiveness of treatment using a needle-free injection system instead of the existing needle injection method in injecting a polynucleotide (PN) filler for skin regeneration.



Professor Hong Ji-yeon and Park Gui-young's team divided their faces into left and right sides of 10 domestic clinical test subjects in this study, injecting polynucleotide (PN) filler injections using traditional needles on one face, and injecting fillers using a needle-free 針 injection system developed by Vaz Biomedic on the other face.

In order to evaluate the patient's skin condition after filler injection, the research team measured pain during filler injection through the Visual Analysis Scale (VAS), along with visual evaluation and 3D skin analysis, and evaluated the subjects' satisfaction and side effects.



As a result, the needleless injection method using CureJet showed higher patient satisfaction and cosmetic improvement than the traditional needle injection method, and the 針 injection showed higher improvement rates at the injection site in wrinkle and pore index improvement, and better results in the Global Aesthetic Improvement Scale (GAIS).

In particular, the 針 injection significantly reduced the patient's pain, and the Visual Analysis Scale (VAS) significantly decreased from 5.4 to 2.9 compared to the needle injection.



As a result, the research team proved that the needle-free '針 syringe' system is more effective in improving pores and wrinkles than the conventional needle injection method in injecting polynucleotide (PN) filler for aging skin regeneration and is also effective in reducing discomfort.

Professor Hong Ji-yeon said, `I think this study will establish a new alternative to a 針 injection system that can solve pain and accuracy problems, which are disadvantages of filler procedures using conventional injection needles""We expect filler procedures using CureJet to be a way to minimize pain and maximize the effect of improving skin aging.""

Professor Park Gui-young said "This study represents an important step forward in the field of non-invasive skin care procedures, suggesting that needleless syringe systems may be preferred for patients with needle phobia or those who want to reduce pain."In addition to reducing pain in the future, we will continue to conduct additional research on pain-free and effective anti-aging procedures as an important achievement that suggests quality improvement and new possibilities for anti-aging procedures."

Meanwhile, the study was published in the latest issue of the internationally renowned SCIE-class journal, the Journal of Cosmetic Dermatology.

'Effective needle-free filler injection for skin aging and wrinkle improvement'
Professors Hong Ji-yeon (left) and Park Gui-young





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