Himchan Hospital "Effective in hospitalization, pain relief during knee arthritis BMAC injection"
Oct 02, 2024
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Artificial joint surgery is the best treatment for knee arthritis when the cartilage is worn out and the pain is severe. As a result, research on treatments that can delay the progression of arthritis as much as possible to help improve pain and knee function and delay the timing of surgery as much as possible is active. Among them, BMAC injection treatment was selected as a new medical technology last year in recognition of its safety and effectiveness by the Ministry of Health and Welfare.
BMAC injection treatment is a method of extracting bone marrow from the iliac crest of the upper pelvis of the patient, separating it by centrifugation using a special kit, and injecting a concentrated bone marrow aspirate containing a large amount of stem cells and growth factors into the knee joint cavity of arthritis patients.
In fact, the number of procedures is gradually increasing as BMAC injection treatment is known as an effective treatment for pain relief and function improvement of knee arthritis, but studies on side effects and complications are still insufficient. This study is significant in that it presents a clinical guide to reduce pain and side effects that patients may experience during the procedure.
A research team on orthopedics at Himchan Hospital, including CEO Lee Soo-chan, Director Baek Ji-hoon (1 author), and Director Nam Chang-hyun (responsible author), compared 40 outpatients and 80 inpatients who received BMAC injection treatment for osteoarthritis from December 2023 to March 2024, with a group of outpatients who performed only local anesthesia and intravenous anesthesia (sleep).
As a result of the study, the average VAS (Visual Analysis Scale) score of the outpatient group was 5.2 points for intubation and 6.2 points for bone marrow aspiration, but the inpatient group showed a big difference of 1.3 points and 1.4 points, respectively, indicating that the pain was mild or no in the inpatient group. The pain evaluation scale selects the intensity of pain felt by the patient from 0 to 10, which means that the closer to 10, the stronger the degree of pain. In addition, temporary complications after treatment were observed in 17.5% of outpatients and 16.3% of inpatients, but both groups resolved within 2 months without any specific problems, and no major complications occurred.
The first author, Baek Ji-hoon, director of Himchan Hospital (Orthopedic Surgeon), said "When treated on the same day, bone marrow is extracted after local anesthesia, and many patients complain of pain at this time. In order to control pain when collecting bone marrow, hospitalization for about a day and intravenous anesthesia (sleep) together is effective in pain management."
In addition, after BMAC injection treatment, knee pain or swelling can sometimes occur due to heparin mixed with BMAC, and inpatients can be treated immediately, but outpatients must return home and return to the hospital. In addition, it is necessary to be hospitalized for several days under the observation of a specialist because there is a possibility of various, if not significant, complications after the procedure."
The study's findings were published in the Journal of Personalized Medicine, a world-renowned SCIE-level international journal, in September.
Director Nam Chang-hyun of Himchan Hospital (Orthopedic Surgeon), the lead author, said "Since BMAC injection treatment was passed as a new medical technology by the Ministry of Health and Welfare in July last year, Himchan Hospital has reported two papers to overseas societies in Korea, the only one in Korea." We will continue to study pain and complications in the future so that patients can be treated more comfortably.'
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