New 'Liquid Polymer Fillers'Eye Wrinkle Improvement Effect
Oct 18, 2024
Professor Kim Bum-joon of the Department of Dermatology at Chung-Ang University Hospital and Professor Choi Sun-young of the Department of Dermatology at Chung-Ang University Gwangmyeong Hospital (Hospital Director Lee Chul-hee) recently published a paper on the results of research on the improvement of wrinkles around the eyes of new liquid polymer fillers.
This study involved a total of 218 patients with wrinkles around the eyes, including a new liquid polycaprolactone (PCL)-based filler DMLR01 (Dexlevo), a test device for wrinkles around both eyes, and polynucleotide (PN)-based filler Rejuran (Rejuran). PharmaResearch) was applied respectively to compare and analyze the effectiveness and safety for a total of 12 weeks.
When DMLR01, a liquid PCL-based filler, was injected, it showed improvement in wrinkles around the eyes at rest at 70.23% after 12 weeks. This showed a similar effect compared to the control device, PN-based filler riser (61.40% improvement rate around the eyes when resting after 12 weeks), and it was confirmed that there were no significant violations in stability.
PCL, one of the main components of fillers, is a medical polymer substance known to help collagen production in the skin. The filler used in this clinical trial was developed as a liquid filler that can be effectively injected into the thin layer of wrinkled skin around the eyes.
Professor Kim Bum-joon and Choi Sun-young's team published a large-scale clinical study in an international journal confirming the effectiveness of PCL-based fillers developed as fillers in the form of liquidated physicochemical properties on wrinkles around the eyes " It is expected that the new liquid PCL-based fillers will contribute greatly to expanding various indications including wrinkles around the eyes" he said.
The research paper of the research team was published in the latest issue of the SCIE-level international journal Journal of Cosmetic Dermatology.
This study involved a total of 218 patients with wrinkles around the eyes, including a new liquid polycaprolactone (PCL)-based filler DMLR01 (Dexlevo), a test device for wrinkles around both eyes, and polynucleotide (PN)-based filler Rejuran (Rejuran). PharmaResearch) was applied respectively to compare and analyze the effectiveness and safety for a total of 12 weeks.
When DMLR01, a liquid PCL-based filler, was injected, it showed improvement in wrinkles around the eyes at rest at 70.23% after 12 weeks. This showed a similar effect compared to the control device, PN-based filler riser (61.40% improvement rate around the eyes when resting after 12 weeks), and it was confirmed that there were no significant violations in stability.
PCL, one of the main components of fillers, is a medical polymer substance known to help collagen production in the skin. The filler used in this clinical trial was developed as a liquid filler that can be effectively injected into the thin layer of wrinkled skin around the eyes.
Professor Kim Bum-joon and Choi Sun-young's team published a large-scale clinical study in an international journal confirming the effectiveness of PCL-based fillers developed as fillers in the form of liquidated physicochemical properties on wrinkles around the eyes " It is expected that the new liquid PCL-based fillers will contribute greatly to expanding various indications including wrinkles around the eyes" he said.
The research paper of the research team was published in the latest issue of the SCIE-level international journal Journal of Cosmetic Dermatology.
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