"Omega-3 Intake improves execution function among cognitive functions"

Oct 22, 2024

'Omega-3 Intake improves execution function among cognitive functions'
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A team led by Kim Ki-woong, a professor of psychiatry at Bundang Seoul National University Hospital, analyzed and announced the impact of cognitive function on omega-3 intake and duration of middle-aged people in their 40s or older.

Omega-3 is a type of fatty acid that contains EPA and DHA as its main components. Ingestion of omega-3 is known to improve lipid, protect blood vessels through anti-inflammatory and antiplatelet actions, promote nerve development and synaptic function, and improve cognitive function. Studies of omega-3 dosage guidelines so far have focused on preventing cardiovascular diseases, and there have been no studies on omega-3 usage in terms of cognitive function management.

In response, Professor Kim Ki-woong's team conducted a study to find out the correlation between omega-3 intake and cognitive function in those in their 40s or older without dementia through meta-analysis using existing studies. Meta-analysis is a method of selecting, analyzing, and summarizing appropriate studies among several studies conducted on a specific topic. Due to the high statistical power, optimal results can be derived for topics showing various research results.



Among 1386 papers related to omega-3, the professor's team selected 24 papers suitable for the study based on ▲ random screening of those in their 40s or older ▲ placebo control ▲ study period of more than 3 months ▲ appropriate cognitive test results. According to the selected papers, 9,660 people were in their 40s or older without dementia, and the study period was 3 months to 36 months, and the daily dose of omega-3 was 230-4000mg. Based on this, a meta-analysis was conducted.

As a result of the study, it was found that omega-3 intake improves execution function, one of the cognitive functions, in those in their 40s or older without dementia. In particular, the effect of improving enforcement function increased during the first 12 months of omega-3 intake, and this effect was remarkable when taking more than 500mg of omega-3 per day or up to 420mg of EPA components per day. Execution function refers to the ability to set goals and plan and control behavior to achieve them by controlling and controlling various sub-cognitive functions.



This study is the first meta-analysis to study the effect of omega-3 intake and duration on execution function after middle age. It is significant in that it not only looked at the relationship between omega-3 and execution function, but also specifically presented omega-3 intake and duration that can have a positive effect on execution function.

Professor Kim Ki-woong said, `If the existing Omega-3 intake guidelines focused on preventing cardiovascular diseases, this study is meaningful in that it revealed omega-3 intake that can manage executive function.'"In addition, increasing intake of omega-3-rich foods such as mackerel, blue-backed fish, eggs, almonds, and tofu in dietary patterns will help maintain a healthy brain.'



Meanwhile, the study was published in the SCIE international medical journal 'BMC Medicine' (IF 9.3).

'Omega-3 Intake improves execution function among cognitive functions'
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