New treatment for intractable keloid scarring reduces wound recovery period by more than 30%
Nov 13, 2024
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A research team led by dermatologists Oh Byung-ho and Jung Jin-woong at Yonsei University Severance Hospital announced on the 13th that if cold therapy is performed immediately after keloid punch resection in refractory keloid scar treatment, the scar score will be less than half after one treatment, and the wound recovery period can be reduced by more than 30% compared to the existing treatment (freezing treatment after central resection).
The findings were published in the international journal Dermatological Surgery.
Kelloid is a protruding scar that extends beyond the area of existing skin damage due to excessive fibrosis. Unlike common scars, they are constantly enlarged and cause pain. Symptoms can be alleviated by conservative treatment such as injection treatment, but surgical treatment is required if the lesion becomes excessively hard. However, even after surgical treatment, keloids may recur or grow in size due to the characteristics of keloids that cause excessive skin reactions to physical forces.
The research team has been actively applying cryotherapy to keloid treatment, considering that keloid scars occur in burn patients but not in frostbite patients. Among the cryotherapy methods, the method performed on the skin surface is less effective, so it was reported in the Journal of the American Academy of Dermatological Surgery in February that the method of excising the central area of keloids and performing cryotherapy immediately was effective. However, this treatment has a limitation in that it takes a long time to heal, although the treatment effect is good.
Through follow-up studies, the research team newly applied cryotherapy by creating several holes in the keloid using a punch used for skin biopsy without removing the entire lesion of the keloid and then spraying liquefied nitrogen refrigerant.
A retrospective analysis study was conducted on 22 intractable keloid patients to analyze the effects of treatment methods. The scar score and recovery period of each group after treatment were compared by dividing the group that underwent immediate cryotherapy after central resection (Group A, 16) and the group that underwent cryotherapy after punch resection (Group B, 6).
Analysis showed that the scar score decreased significantly in both groups from 8.13±1.05 before treatment to 4.00±1.00 after treatment in group A and 3.67±0.94 after treatment in group B from 7.83±0.37 before treatment. On the other hand, the recovery period for wounds after treatment was 63.87±29.80 days in group A and 43.5±14.93 days in group B, which was more than 30% shorter than group A.
Professor Byung-ho Oh "Through this study, a new treatment method that can significantly reduce the recovery period as well as relieve scarring in the treatment of refractory keloid patients."We plan to conduct additional research to standardize treatment methods so that we can provide high-quality treatment to more patients. "
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