The effect of prolonging the survival period of pancreatic cancer patients with herbal medicine dry skin and chemotherapy
Jan 05, 2025
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◇Check the effectiveness of herbal medicine 'dry' for patients with advanced pancreatic cancer
An oriental medicine research team at Gangdong Kyunghee University Oriental Medicine Hospital (Professor Yoon Seong-woo, researcher Jin Ha-yoon) and a gastroenterology research team at Gangdong Kyunghee University Hospital (Professor Joo Kwang-ro and Professor Park Nam-young) conducted a clinical study on advanced pancreatic cancer patients who began receiving first-line chemotherapy because surgery was impossible.
The results were recently published in the international journal 'Frontiers in Oncology'.
The research team analyzed the factors affecting the survival period of patients with advanced pancreatic cancer undergoing chemotherapy. As a result of the study, it was confirmed that the survival period increased significantly as the dose of the dry lacquer extract administered to the patient increased. As a result of multivariate analysis, the risk ratio due to the increase in the volume of the dry lacquer extract was 0.18 in the disease-free survival period and 0.01 in the overall survival period.
Professor Yoon Seong-woo's team said that the dosage of herbal medicine dried lacquer extract was identified as an independent prognostic factor affecting the prognosis of pancreatic cancer patients. In addition, this study is an early study on the safety and effectiveness of standard chemotherapy and herbal medicine combination administration, and large-scale research is needed in the future.
◇ Research on combination administration of anticancer drugs and herbal medicines, safety verification is the top priority
The research team of oriental medicine and gastroenterology conducted the verification with safety as they performed dry lacquer extract and chemotherapy at the same time.
As a result of the study, when administered together with anticancer drugs, there was no effect of reducing the effectiveness of anticancer drugs or increasing side effects. In particular, liver and renal function tests were also followed up and analyzed in consideration of concerns about toxicity to the liver and kidneys of herbal extracts. Both liver and kidney function levels before and after treatment showed no abnormalities.
◇ Lacquer tree 'Dry' Immunofunction Anti-inflammatory action already verified
Lacquer tree dry lacquer is a medicinal ingredient that also records the effect of improving hemoptysis, a symptom of blood clumping, in Dongui Bogam.
As a drug widely used in modern times, continuous research is underway as the effect of improving immune function and anti-inflammatory action has already been confirmed through various cell and animal experiments. However, there was a limitation that it contained a component that could cause a severe allergic rash known as 'lattox'. The drug used in this study is developed by Kyung Hee University Oriental Medicine Hospital by extracting only safe and effective ingredients except for the allergy rash ingredients of dry skin.
◇"A study that can give hope to cancer patients…Validated Drug Administration Critical"
Professor Yoon Seong-wu said "The dried lacquer used in the study has been used as herbal medicine for a long time, and various studies have already confirmed the effect of suppressing various types of cancer and extending the survival period of cancer patients."This is the first prospective clinical study to administer dry lacquer extract to patients undergoing chemotherapy, and it has achieved a safe and hopeful result that extends survival period" he explained.
However, Professor Yoon emphasized that in order to safely perform both chemotherapy and herbal medicine, medical institutions should administer proven medicines while conducting close follow-up tests in consultation with medical staff specializing in oriental medicine. In particular, he advised that cancer patients undergoing chemotherapy should approach parallel treatment more carefully as various side effects from cancer and cancer treatment may occur.
The study was conducted as part of the Korean Institute of Health and Industry Development's oriental medicine innovation technology development project under the Ministry of Health and Welfare.
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This article was translated by Naver AI translator.
