Obesity drugs are effective but cause muscle loss...How to lose weight wisely?

Jan 31, 2025

Obesity drugs are effective but cause muscle loss...How to lose weight wisely?
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Obesity is not just a problem of appearance, but a serious health problem that can cause chronic diseases such as high blood pressure, diabetes, and cardiovascular disease, and constant management is essential. In the new year, more and more people are considering obesity treatment or surgery, which is a recent craze, to lose weight in a short period of time. Medical staff emphasize that drugs and surgery are very effective treatments, but healthy lifestyle improvements must be combined for long-term success.

Kwon Young-geun, a professor at Korea University's Anam Hospital's Obesity Ambassador Center, said "Drug treatment or surgery is an important tool for obesity treatment and a very effective method"However, lifestyle changes are essential to maintain the weight loss effect obtained through this in the long term." He stressed that it is important to maintain weight through steady efforts, not short-term changes.

◇New obesity treatment is effective, but there is a concern about yo-yo...It also causes muscle loss




Drugs that are currently attracting attention among obesity treatments are Hugo Bee and Maunzaro. Both drugs are of the GLP-1 analog family, which suppresses appetite and aids in weight loss. The stomach fat is used for obese patients with a body mass index (BMI) of 30kg/m2 or more, or patients with weight-related comorbidities such as high blood pressure and diabetes with a BMI of 27kg/m2 or more and less than 30kg/m2, with an average weight loss effect of 15%. Mounzaro is known to lose up to 22.5% of weight.

However, medication can lead to muscle loss, not just fat removal.

Professor Kwon Young-geun explained "In order to lose weight, a diet rich in protein, vitamins, and minerals and regular muscle exercise must be combined to prevent muscle loss and prevent the reduction of basic metabolism." In addition, it is important to establish healthy eating and exercise habits while using the drug, as discontinuation of drug treatment can result in yo-yo phenomenon.




Obesity metabolic surgery is considered first if obesity-related comorbidities are reliably treated and subsequently drug treatment failures are experienced. Typical obesity surgeries include gastrectomy and gastric bypass surgery. Gastric sleeve resection limits food intake by reducing gastric volume, and gastric bypass shortens the digestion process, reducing food absorption. In addition to weight loss, these operations have the advantage of improving comorbidities such as diabetes, hypertension, hyperlipidemia, and fatty liver, and less worry about yo-yo than drugs.

Professor Kwon Young-geun said, "More than 95% of people lose weight after surgery, but lifestyle improvements are essential to maintain weight. "To maintain the effects of surgery, you need to eat a nutrient-rich diet and exercise together."," he stressed.

◇The key to obesity treatment is improving lifestyle...You need to eat and exercise at the same time




Professor Kwon added, `All obesity treatments, including drugs and surgery, cannot guarantee long-term success without healthy lifestyles", he pointed out. The most important thing in the treatment of obesity is to maintain a sustainable lifestyle even after losing weight. It is important to maintain muscle mass by eating a diet rich in protein and vitamins and performing muscle strength exercises in parallel.

"If you are determined to go on a New Year's diet, it is important to set small goals that can be practiced consistently so that it does not end in three days of determination." Avoiding rapid weight loss and achieving goals slowly but steadily will help your health in the long run."," he added.

Obesity drugs are effective but cause muscle loss...How to lose weight wisely?
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This article was translated by Naver AI translator.