Vaccines, Anti-Inflammatory Drugs Lower Dementia Risk by 32%…Additional study of authorized drugs is required

Jan 22, 2025

Vaccines, Anti-Inflammatory Drugs Lower Dementia Risk by 32%…Additional study of authorized drugs is required
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Studies have shown that anti-inflammatory drugs such as ibuprofen can reduce the risk of dementia.

A joint research team from the University of Cambridge and the University of Exeter in the UK has already confirmed that several drugs in use with permission are likely to be used to treat dementia.

The findings were recently published in the journal 『Alzheimer's and Dementia: Translational Research and Clinical Interventions』.




The research team synthesized and analyzed health and prescription data for 130 million people worldwide and 1 million dementia cases.

Results showed that hepatitis A vaccine, typhoid vaccine, combination vaccine, and diphtheria vaccine reduced the risk of dementia by up to a third (32%).

Previous studies have reported that BCG vaccines that prevent tuberculosis have the potential to prevent Alzheimer's disease.




However, the researchers pointed out that it is 'too early' to conclude whether these drugs can have protective effects, and further research is needed.

Dr. Ben Underwood of Cambridge University's Department of Psychiatry said there is an urgent need for new treatments to slow the progression of dementia, although they may not prevent it.

He stressed that "If we can find it in drugs that are already authorized for other diseases, we will be able to bring them into clinical trials and, crucially, provide drugs to patients much faster than developing entirely new drugs."






This article was translated by Naver AI translator.