cerebrovascular disease accelerates cognitive decline of middle-aged and elderly people...Inducement of stroke, dementia, etc

Feb 18, 2025

cerebrovascular disease accelerates cognitive decline of middle-aged and elderly people...Inducement of stroke, dementia, etc
자료출처=The Lancet Regional Health-Western Pacific



Domestic researchers have identified the relationship between cerebrovascular disease and cognitive decline.

A research team led by Professor Shin Cheol of Korea University School of Medicine (Human Genomics Research Institute) has revealed the relationship between cerebrovascular disease (cSVD) and cognitive decline in middle-aged and elderly people. This study is a large cohort study conducted from 2011 to 2022 that compared brain magnetic resonance imaging (MRI) and cognitive ability before and after 8 years of cognitive ability in 2,454 adults aged 49 to 79.

According to the results of the study, 37% of the study participants had cerebrovascular disease, and they showed distinct differences in concentration and memory loss compared to the group without cerebrovascular disease. In particular, cognitive decline in the group with cerebrovascular disease has been shown to accelerate over time.




Cerebral vascular disease is a disease that occurs when small blood vessels in the brain are damaged or blocked, and can gradually deteriorate brain function.

The main causes include high blood pressure, diabetes, smoking, and sleep apnea. Unlike macrovascular disease, which causes acute stroke or bleeding, cerebrovascular disease may have minimal or ambiguous symptoms in the early stages. If symptoms such as hand tremors, slow walking, speech disorders, and paralysis of one mouth or hand and foot appear microscopic, you should visit a hospital immediately.

Professor Shin Cheol of Korea University Medical School said, `In middle-aged and elderly people, cerebrovascular disease is closely associated with cognitive decline"Especially, there was a noticeable difference in concentration and memory, which are execution functions. People with underlying diseases such as high blood pressure or diabetes associated with sleep apnea are at increased risk of cerebrovascular disease, so early diagnosis and management are essential."




If cerebrovascular disease is left unattended, it should be actively dealt with because it can lead to more serious sequelae such as dementia or walking disorders. In particular, people over the age of 45 or with underlying diseases such as high blood pressure and diabetes can detect cerebrovascular disease early through regular brain health checks and detailed examinations. In addition, proper treatment and lifestyle improvements can slow progression to serious conditions such as stroke, cognitive decline, and dementia.

Meanwhile, the study was conducted as a Korean Genome Epidemiology Survey Project (KoGES) organized by the National Institute of Health of the Korea Centers for Disease Control and Prevention, and the results of the study were published in the February 2025 issue of The Lancet Regional Health-West Pacific, a sister paper of the global medical journal 'The Lancet'.

cerebrovascular disease accelerates cognitive decline of middle-aged and elderly people...Inducement of stroke, dementia, etc
신철 교수





This article was translated by Naver AI translator.