Hepatic diagnostic reference point for hardening...Expected improvement in diagnostic accuracy of liver fibrosis
Mar 02, 2025
A reference point was presented to accurately check the degree of hardening of the liver in patients with fatty liver with metabolic abnormalities.
Professor Kim Seung-up of the Department of Gastroenterology at Severance Hospital, Professor Yoo Jeong-hwan of the Department of Gastroenterology at Inha University Hospital, and Professor Jeon Young-eun of the Department of Gastroenterology at Bundang Cha Hospital said on the 27th that the research team has identified the most suitable reference point for diagnosing advanced liver fibrosis, in which the liver hardens in patients with metabolic fatty liver disease.
The results of this study were published in the journal of the Korean Liver Association 'CMH (Clinical and Molecular Hepatology, IF 14)'.
Metabolic fatty liver disease is a disease in which fat accumulates in the liver with metabolic diseases such as high blood pressure and high blood sugar. If it progresses to severe liver disease or worsens, it can also lead to liver cancer. Moreover, regular checkups are a very important disease because symptoms are not clear and it is difficult to detect early. At this time, fibrosis, in which the liver hardens, is important in measuring the prognosis of metabolic abnormal fatty liver disease.
The research team analyzed all existing research results to confirm the optimal criteria for diagnosing metabolic abnormal fatty liver disease in order to increase the accuracy of the most recently studied non-invasive liver fibrosis diagnostics, 'instantaneous elasticity measurement method' and 'magnetic resonance elasticity measurement method'.
The research team analyzed data from 19,000 instantaneous elasticity measurement methods and 1,400 magnetic resonance elasticity measurement methods out of 72 documents that were judged to be suitable for the study.
The results revealed that 7.1 to 7.9 kPa (kilopascals) for instantaneous elasticity measurements and 3.62 to 3.8 kPa (kilopascals) for magnetic resonance elasticity measurements are the best reference points for diagnosing advanced liver fibrosis in patients with metabolic abnormal fatty liver disease.
Professor Kim Seung-up, the head of the study, said "The number of patients with metabolic abnormal fatty liver disease is on the rise recently, but there is a lack of practical information on non-invasive testing methods" and "This study allowed us to present new criteria that can be used for patient care in clinical practice"
Professor Kim Seung-up of the Department of Gastroenterology at Severance Hospital, Professor Yoo Jeong-hwan of the Department of Gastroenterology at Inha University Hospital, and Professor Jeon Young-eun of the Department of Gastroenterology at Bundang Cha Hospital said on the 27th that the research team has identified the most suitable reference point for diagnosing advanced liver fibrosis, in which the liver hardens in patients with metabolic fatty liver disease.
The results of this study were published in the journal of the Korean Liver Association 'CMH (Clinical and Molecular Hepatology, IF 14)'.
Metabolic fatty liver disease is a disease in which fat accumulates in the liver with metabolic diseases such as high blood pressure and high blood sugar. If it progresses to severe liver disease or worsens, it can also lead to liver cancer. Moreover, regular checkups are a very important disease because symptoms are not clear and it is difficult to detect early. At this time, fibrosis, in which the liver hardens, is important in measuring the prognosis of metabolic abnormal fatty liver disease.
The research team analyzed all existing research results to confirm the optimal criteria for diagnosing metabolic abnormal fatty liver disease in order to increase the accuracy of the most recently studied non-invasive liver fibrosis diagnostics, 'instantaneous elasticity measurement method' and 'magnetic resonance elasticity measurement method'.
The research team analyzed data from 19,000 instantaneous elasticity measurement methods and 1,400 magnetic resonance elasticity measurement methods out of 72 documents that were judged to be suitable for the study.
The results revealed that 7.1 to 7.9 kPa (kilopascals) for instantaneous elasticity measurements and 3.62 to 3.8 kPa (kilopascals) for magnetic resonance elasticity measurements are the best reference points for diagnosing advanced liver fibrosis in patients with metabolic abnormal fatty liver disease.
Professor Kim Seung-up, the head of the study, said "The number of patients with metabolic abnormal fatty liver disease is on the rise recently, but there is a lack of practical information on non-invasive testing methods" and "This study allowed us to present new criteria that can be used for patient care in clinical practice"
|
This article was translated by Naver AI translator.
